OMEGAL DHA

What are Omega-3?

Omega-3s are a category of essential polyunsaturated fatty acids that our body is unable to synthesize and which must therefore necessarily be taken through the diet. All Omega-3s support the anti-inflammatory function, while the Omega-6s support the pro-inflammatory one. Maintaining a correct Omega-3 / Omega-6 ratio is of fundamental importance in order to maintain their properties unaltered in the prevention of some pathological conditions. The main Omega-3s are: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

Why take DHA?

The role of Omega-3 fatty acids in the brain and retina is structural: they help maintain a highly fluid membrane environment. DHA makes up more than 30% of the structural lipids of brain cells and up to 60% of those of the retina. Due to a lifestyle that is increasingly oriented towards optimizing the time factor, we tend to adopt a diet poor in Omega-3, in particular DHA, without realizing it.

DHA has been defined by some authors as a real neurotrophic factor. In fact, at the hippocampus level, DHA favors the biosynthesis of a neurotrophic factor called "brain-derived neurotrophic factor (BDNF)", a factor involved in the stimulation of neuronal plasticity, through the induction of synaptic proteins. Through this mechanism, DHA, favoring the formation of synapses in the hippocampus, contributes to the maintenance of neuronal plasticity, cognitive functions and memory.

The role of DHA in the visual process is essential for the normal functioning of rhodopsin and guarantees elastic properties to the cells of the retina. Numerous studies have shown a correlation between low DHA levels and pigment retinitis. Dietary supplementation with DHA reduces degeneration and increases retinal function. DHA slows the development of retinitis pigmentosa and age-related macular degeneration (AMD).

Knowing the exponential rate of brain cell division that occurs in the fetus or in the first year of life, it is possible to imagine the great replicative drive brought about by a diet rich in Omega-3 fatty acids. During the last phase of gestation and the postnatal period, the development of the nervous system is exceptionally rapid and the nutritional inputs of polyunsaturated fatty acids (PUFA), in particular DHA, are critical to ensure proper development of the brain and retina.

Intake of adequate levels of DHA during pregnancy and breastfeeding is therefore important to ensure proper fetal development and growth of the baby.

What is OMEGAL DHA?

OMEGAL DHA is a food supplement based on DHA, a polyunsaturated fatty acid of the Omega-3 series completely vegetable obtained from a fermentation process of microalgae of the Schizochytrium species.

The main problem of oils rich in Omega-3 is represented by the high sensitivity to oxidation caused by agents such as air, temperature, water, etc. It is therefore of fundamental importance to be able to preserve the organoleptic and nutritional properties and the average life span of Omega-3s.

Thanks to the exclusive patented technology enjoyed by the algal oil contained in OMEGAL DHA, the oxidation state of Omega-3s is kept under control, considerably increasing their stability. The nutritional and organoleptic qualities of Omega-3 are thus effectively preserved over time.

Each capsule of your OMEGAL DHA will maintain the same purity and stability until the expiration date.

Main properties of Omegal DHA components?

The antioxidant and nourishing action of DHA allows you to enjoy numerous health benefits in the event that dietary intake is insufficient. The beneficial effect of Omegal DHA involves three main therapeutic categories:

• Brain function (the beneficial effect is obtained by taking a daily dose of 250 mg of DHA)

• Visual capacity (the beneficial effect is obtained by taking a daily dose of 250 mg of DHA)

• Pregnancy and breastfeeding (the beneficial effect is obtained by taking a daily dose of 250 mg of EPA and DHA)

Functional component

DHA (Docosahexaenoic acid)

Daily dose and method of administration

Each capsule of Omegal DHA contains 250 mg of DHA.

Take 1 capsule per day at any time of the day.

Also indicated in vegetarian and vegan diets.

Allergens

Omegal DHA is allergen free.

Warnings

Food supplements are not intended as a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of the reach of children under 3 years of age. Do not take in case of hypersensitivity or allergies to one or more components.

Conservation rules

Store in a cool and dry place, at a temperature not exceeding 25 ° C, away from light and / or heat sources. The minimum storage term refers to the product correctly stored in an unopened package.

Package Format

Pack of 40 soft gel capsules of 850 mg.

References

Joffre C et al. 2014 LCPUFA improves cognition: the young, the old and the sick. Prostaglandins Leukot Essent Fatty Acids,91, 1-20.
Marszalek JR, et al. 2005. Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you. Annu. Rev. Cell Dev. Biol. 21:633–57.
McNamara RK et al., 2010 Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging,
functional magnetic resonance imaging study Am. J. Clin. Nutr., 91, 1060–1067.
Nourooz-Zadeh J, et al. 1999. F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease. Journal of Neurochemistry, 72, 734-740.
Stonehouse W. et al., 2013 DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial. Am. J. Clin. Nutr., 97 1134–1143.
Ulmann L, et al. 2001. Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats. Prostaglandins Leukot Essent Fatty Acids. 64:189-95.
US Department on health and Human services - National Institute on Aging
Yehuda S, et al. 2000. Fatty acids mixture counters stress changes in cortisol, cholesterol, and impair learning. Int. J. Neurosci. 101:73-87.
Yehuda S, et al. 2002. The role of polyunsatured fatty acids in restoring the aging neuronal membrane. Neurobiol. Aging. 23:843-53.
Wu A, et al. 2008. Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition. Neuroscience 155:751–9.
Wurtman RJ. 2008. Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. Metabolism 57:S6–S10.
Freemantle E, et al. 2006. Omega-3 fatty acids, energy substrates, and brain function during aging. Prostaglandins Leukot Essent Fatty Acids 75:213–20.
11. Hooijmans CR, et al. 2009. DHA and cholesterol containing diets influence Alzheimer like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice. Neurobiol
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